def difference_by(a, b, fn):
  _b = set(map(fn, b))
  return [item for item in a if fn(item) not in _b]
from math import floor

difference_by([2.1, 1.2], [2.3, 3.4], floor) # [1.2]
difference_by([{ 'x': 2 }, { 'x': 1 }], [{ 'x': 1 }], lambda v : v['x']) # [ { x: 2 } ]

 

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